Micronucleus & Cytokinesis-Block Genotoxicity
Detects micronuclei and related nuclear abnormalities in mononucleated or cytokinesis-blocked binucleated cells.
- Ch1: DAPI, Hoechst, or another DNA stain
- Optional Ch2: cytoplasmic or cell-boundary marker
- Optional cytokinesis-block treatment metadata such as cytochalasin B
- Micronuclei count per cell
- % micronucleated cells
- % micronucleated binucleated cells
- Binucleated-cell count and fraction
- Nuclear bud count
- Nucleoplasmic bridge count
- Nuclear division or cytokinesis-block index where assay design supports it
Everything you need for micronucleus & cytokinesis-block genotoxicity
Automated, reproducible, and code-free analysis in the cloud
Cloud-based
No software to install, no GPU required. Run analysis from any browser on any device.
Fully automated
Upload your images and get publication-ready results. No coding or scripting needed.
Reproducible
Every analysis is logged and reproducible. Share protocols with collaborators instantly.
How it runs
Cytely automates the image analysis so you can focus on the science.
Segment primary nuclei
Group nuclei by cell boundary or proximity
Classify mononucleated and binucleated cells
Detect smaller separate DNA-positive bodies using morphology and distance rules
Score micronuclei and related abnormalities per eligible cell.
Compatibility
Ready to run
Conventional micronucleus counting, cytokinesis-block micronucleus (CBMN), mononucleated-cell scoring, nuclear buds, nucleoplasmic bridges, integration with γH2AX or other damage markers.
Inquire for support
Comet-assay head/tail morphometry, chromosome-specific micronucleus content without additional probes, or automated regulatory interpretation without assay-specific controls and validation.
1 Dependent on sample quality
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