Immunology Lab, Lund University
From false positives to MOA-verified hits with visual phagocytosis screening.
Challenge
- Flow cytometry stripped adherent macrophages (changing their biology) and produced false positives from dye transfer
- Cannot verify true phagocytosis vs. surface contamination
- Need for complex coding to automate
Solution
- Image-based analysis preserves adherent cell biology with visual verification of internalization
- Browser-based interface - no programming required
- Population gating distinguishes true double-positives from artifacts
Key Benefits
Caught
artifacts flow cytometry missed
Linked
binding to function—visual proof of mechanism
Eliminated
bioinformatics bottleneck
Ready to accelerate your research?
Book a call with our team to discuss how Cytely can help solve your microscopy analysis challenges.