Immunology Lab, Lund University
시각적 식균작용 스크리닝으로 위양성에서 MOA가 검증된 유효 후보로 나아갔습니다.
과제
- Flow cytometry stripped adherent macrophages (changing their biology) and produced false positives from dye transfer
- Cannot verify true phagocytosis vs. surface contamination
- Need for complex coding to automate
솔루션
- Image-based analysis preserves adherent cell biology with visual verification of internalization
- Browser-based interface - no programming required
- Population gating distinguishes true double-positives from artifacts
주요 이점
Caught
유세포 분석이 놓친 인공물(artifact)
Linked
결합에서 기능으로—메커니즘의 시각적 증거
Eliminated
생물정보학 병목